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A translational research approach combining human and animal models of hearing

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Overview

The primary interest of our lab is in understanding how the peripheral auditory system and the central auditory pathway interact in various forms of hearing loss. The research program integrates study of human clinical populations and animal models, using non-invasive, EEG-like evoked potentials as the translational bridge. The overall goal is to inform diagnosis and track the benefits of interventional therapies in clinical populations with hearing loss by utilizing insights obtained from animal models with similar forms of pathology.

Locations

We are a part of the Department of Communication Science and Disorders at the University of Pittsburgh, located in Pittsburgh, Pennsylvania. 

Work in human clinical populations is conducted at the lab spaces within the Brain and Auditory Sciences Research Initiative (BASRI)  at Forbes tower. This multi-use multi-PI research initiative space fosters close collaboration between various researchers in hearing and speech, and provides access to shared equipment and resources. BASRI contains multiple EEG systems and eye trackers within sound chambers and various multi-purpose rooms for behavioral testing. 

Work in rodent models of hearing loss is conducted at the scenic Bridgeside Point 1, a newly designed, state-of-the-art lab space for animal research within the CSD department. In addition to a dedicated space for neurophysiology, we also have access to a shared, fully equipped wet lab space and a microscopy suite.